ImmunoSept - Personalized immunotherapy in sepsis: a precision medicine based approach
In order to introduce successful precision medicine in the treatment of sepsis, ImmunoSep pursues the following key objectives: 1) Design and conduct a large proof-of-concept randomised controlled trial to provide answers about the usefulness of personalised immunotherapy for sepsis patients. 2) Perform an integrated, multi-dimensional systems biology analysis of omics-based datasets, to identify biomarkers, clinical endotypes, and therapeutic targets needed for future precision medicine approaches. 3)Set up a new theranostics platform to help develop next-generation clinical trials through improved patient stratification and treatment allocation. 4) Integrate novel immunotherapeutic approaches into health systems through close collaboration with professional and patient organisations.